American Express Co., the largest credit- card issuer by purchases, said it will cut 45 jobs in its enterprise growth unit next year as part of a reorganization.

The reductions will take place between Feb. 19 and May 13, AmEx said in a so-called WARN notice dated Nov. 20 and filed with the New York Department of Labor.

Marina Norville, a spokeswoman for the New York-based lender, didn’t immediately respond to a request for comment.