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How to Reverse Type 2 Diabetes: Expert

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By    |   Wednesday, 13 Sep 2017 12:11 PM

Type 2 diabetes can be reversed even if you've had it for a decade, says Roy Taylor of the U.K.'s Newcastle University. Taylor has spent four decades examining the underlying causes of diabetes, and claims it is reversible.

Taylor says his research confirms his Twin Cycle Hypothesis — that Type 2 diabetes is caused by too much fat in both the liver and the pancreas.  

He found that too many calories lead to too much fat in the liver. As a result, the liver doesn't respond as well to insulin, and produces too much glucose.

Excess fat in the liver is sent to other areas of the body, including the pancreas, causing the cells that produce insulin to fail.

But he has also found that losing less than 1 gram of fat in the pancreas — even 10 years after the onset of diabetes — can restart the normal manufacture of insulin and reverse Type 2 diabetes.  

"I think the real importance of this work is for the patients themselves," Taylor says. "Many have described to me how embarking on the low-calorie diet has been the only option to prevent what they thought — or had been told — was an inevitable decline into further medication and further ill health because of their diabetes."

Taylor's work showed an extreme drop in the amount of fat in the liver in people with Type 2 diabetes which resulted in the normalization of insulin sensitivity within seven days of starting a very low-calorie diet.

Fasting plasma glucose became normal in seven days. Over eight weeks, the amount of fat in the pancreas fell, and it began to produce insulin normally, which allowed the body to control sugar levels.

"The good news for people with Type 2 diabetes is that our work shows that even if you have had the condition for 10 years, you are likely to be able to reverse it by moving that all important tiny amount of fat out of the pancreas," said Taylor. "At present, this can only be done through substantial weight loss.

"Surprisingly, it was observed that the diet devised as an experimental tool was actually liked by research participants," he said. "It was associated with no hunger and no tiredness in most people, but with rapidly increased wellbeing."

His weight-loss approach is a two-phase program. Phase 1 is the period of weight loss and consists of calorie restriction without additional exercise. Phase 2 is long-term weight maintenance with modest calorie restriction and increased physical activity.  

Another recent study conducted by researchers at the University of Texas Health Science Center at San Antonio cured Type 1 diabetes in mice without side effects. The treatment would also allow people with Type 2 diabetes to stop insulin shots.

The therapy uses a technique called gene transfer to increase the number of pancreatic cells that secrete insulin. A virus is used as a carrier to introduce selected genes into the pancreas. These genes become incorporated into the organ and cause digestive enzymes and other cell types to make insulin.

According to the Centers for Disease Control and Prevention, 29.1 million Americans had diabetes in 2014.

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Type 2 diabetes can be reversed even if you've had it for a decade, says Roy Taylor of the U.K.'s Newcastle University. Taylor has spent four decades examining the underlying causes of diabetes, and claims it is reversible.Taylor says his research confirms his Twin Cycle...
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2017-11-13
Wednesday, 13 Sep 2017 12:11 PM
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