Dr. Russell Blaylock, author of The Blaylock Wellness Report newsletter, is a nationally recognized board-certified neurosurgeon, health practitioner, author, and lecturer. He attended the Louisiana State University School of Medicine and completed his internship and neurological residency at the Medical University of South Carolina. For 26 years, practiced neurosurgery in addition to having a nutritional practice. He recently retired from his neurosurgical duties to devote his full attention to nutritional research. Dr. Blaylock has authored four books, Excitotoxins: The Taste That Kills, Health and Nutrition Secrets That Can Save Your Life, Natural Strategies for Cancer Patients, and his most recent work, Cellular and Molecular Biology of Autism Spectrum Disorders. Find out what others are saying about Dr. Blaylock by clicking here.
Tags: bioavailability | vitamin C | CoQ10 | nanosizing

Improving Supplement Absorption

Wednesday, 22 July 2015 04:45 PM Current | Bio | Archive

Bioavailability refers to the ability of a drug or supplement to get to cells or tissues, where it can produce the beneficial effects that people want.

Because bioavailability is so critical to the effective use of supplements, a number of new methods for improving absorption and distribution of supplements have been created by some of the more innovative companies.

For example, we know that there is a limit to the amount of vitamin C that can be absorbed and retained by the body.

Once this limit is reached, the rest is excreted into the bowel. (This is why high vitamin C intake can result in diarrhea.)

To overcome this response, scientists encapsulated the vitamin C molecules in microscopic capsules of fat (usually phospholipids such as phosphatidylcholine). This allows a much higher concentration of vitamin C to be absorbed by the body.

Vitamin C itself is water-soluble, and inside cells it is limited to the watery parts of the cells. But lipid-encapsulated vitamin C can enter the membrane of other compartments of the cell, where it can provide even more protection.

Another way to improve bioavailability is to break supplement molecules into much smaller parts.

Most supplements exist as clumps of molecules, which can make them difficult to absorb. But when they are broken down into micron-size particles, it can greatly improve absorption.

Indeed, there are now even smaller, nanosize particles, available for some supplements — making them even more bioavailable. This also allows people to use smaller doses of supplements because more of the active substances are getting to the beneficial area of the body — even the brain — than would if the supplement were consumed in a powder form.

For example, 100 mg of the nanosize form of coenzyme Q10 (CoQ10) is equivalent to several
hundred milligrams of the older powdered product.

Nanosizing can also turn a lipid-soluble supplement into one that dissolves both in lipids and water, which greatly improves gut absorption and distribution in the body.

Nanosizing also overcomes one of the biggest problems for users of natural products — getting
beneficial substances into the brain.

Nanosize products can reach much higher levels in the brain, entering all parts of brain cells better than conventional forms.

Because nanosizing so greatly improves the absorption of poorly absorbed products, such as many of the flavonoids, it means that supplements can be put in smaller capsules.

This means that users can obtain equal or even better results with smaller, less expensive doses than they do when using traditional supplements.

© 2019 NewsmaxHealth. All rights reserved.

1Like our page
A number of new methods for improving absorption and distribution of supplements have been created by some of the more innovative companies.
bioavailability, vitamin C, CoQ10, nanosizing
Wednesday, 22 July 2015 04:45 PM
Newsmax Media, Inc.

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

© Newsmax Media, Inc.
All Rights Reserved