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Frozen Ovary Tissue From When She Was 13 Lets Mom Give Birth

By    |   Thursday, 11 Jun 2015 08:30 AM

Doctors recently used frozen ovary tissue removed from a Belgium immigrant when she was 13 to restore her fertility and allow her to give birth 14 years later.

A report published in the medical journal Human Reproduction said it was the first time a birth resulted from ovarian transplantation of a subject using frozen ovary tissues taken before puberty, according to a release from the European Society of Human Reproduction and Embryology.

 


There has been documented success of ovarian transplantation when scientists used tissue from patients taken when they were already adults, noted the reproduction organization.

"This is an important breakthrough in the field because children are the patients who are most likely to benefit from the procedure in the future," said Dr. Isabelle Demeestere.

Demeestere, a gynecologist and research associate in the Fertility Clinic and Research Laboratory on Human Reproduction at Erasme Hospital at the Université Libre de Bruxelles in Brussels, said the successful birth was a breakthrough but needs following up.

"When they are diagnosed with diseases that require treatment that can destroy ovarian function, freezing ovarian tissue is the only available option for preserving their fertility," Demeestere continued. "However, the success of this procedure requires further investigation in very young, pre-pubertal girls, as our patient had already started puberty even although she had not started menstruating."

The patient, who came to Belgium from the Republic of Congo, was 27 when she gave birth to a healthy boy in November 2014, according to the BBC News. She had an ovary removed and frozen at 13 after receiving treatment for sickle cell anemia.

The sickle cell treatment included a bone marrow transplant and chemotherapy and her remaining ovary failed at 15.

Adam Balen, chairman of the British Fertility Society, told BBC News the successful ovary transplantation and following birth marks a positive milestone in fertility research.

"One would anticipate that young ovaries should have lots of eggs in them, the concern was whether those eggs might develop to maturity, if the ovarian tissue was taken at such a young age and frozen and then re-implanted," said Balen. "So, this is proof of that concept... it's very important information."


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Doctors recently used frozen ovary tissue removed from a Belgium immigrant when she was 13 to restore her fertility and allow her to give birth 14 years later.
frozen, ovary, tissue, lets, mom, give, birth
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2015-30-11
Thursday, 11 Jun 2015 08:30 AM
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