Testosterone treatment in men with "low T" has been shown to cut their heart disease risk.
According to new research by the Boston University School of Medicine, "low T" therapy helps improve cholesterol, blood pressure, and glucose levels in men who are deficient in the male hormone — lowering their risk of developing diabetes and boosting their cardiovascular health.
"In addition to improving their cholesterol levels, we found that the testosterone treatment resulted in marked reductions in systolic and diastolic blood pressure as well, suggesting amelioration of hypertension," said Abdulmaged M. Traish, a professor of biochemistry and urology who led the study, published online in the International Journal of Clinical Practice.
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Past studies have found men with low testosterone levels are prone to metabolic disorders, insulin resistance, diabetes, and hypertension. Obese and overweight men are also more likely to have "low T."
For the new study, researchers tracked 255 men given testosterone treatment for five years.
They found that men treated with testosterone therapy had a gradual reduction of their total cholesterol, low density lipoprotein cholesterol (LDL "bad" cholesterol), triglycerides, and increased high density lipoprotein (HDL "good" cholesterol. The treatment also reduced fasting blood glucose and hemoglobin A1C levels — key markers of diabetes — as well as markers of inflammation tied to heart and liver disease.
"These data are congruent with our previous work in which we reported that long-term testosterone resulted in a gradual decline in weight and waist circumference and strongly suggests that testosterone therapy in ['low T'] men may prove useful in reducing the risk of cardiometabolic diseases," Traish added.
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