Tags: tb | antibiotic | drug | resist

Natural Antibiotic Kills TB: Research

Wednesday, 19 Sep 2012 12:57 PM


A natural antibiotic found in bacteria and soil is showing promise as a potential new drug to treat tuberculosis, which is becoming increasingly resistant to drugs against it.

In a study published in the European Molecular Biology Organization journal Molecular Medicine, a team of scientists working in Switzerland has determined pyridomycin – a natural antibiotic produced by the bacterium Dactylosporangium fulvum – is a potent weapon against many of the drug-resistant TB strains that have raised public health officials' concerns.

"Nature and evolution have equipped some bacteria with potent defense mechanisms to protect them against other bugs that share their habitat. Screening natural products generated by these organisms is therefore a powerful way to find possible new drugs to fight infectious diseases," said lead researcher Stewart Cole, a professor at the École Polytechnique Fédérale de Lausanne.

Wheat Belly: #1 Diet and Health Book in America Changing Lives - ONLY $4.95! Save $21!

"Using this approach we have shown that nature's antibiotic pyridomycin is a very selective killer of Mycobacterium tuberculosis, the bacterium responsible for tuberculosis in humans. It is also active against mycobacteria that have developed resistance to front-line drug treatments such as isoniazid."

Tuberculosis causes up to two million deaths annually and public health experts around the world have become concerned that many drugs are no longer effective in treating it. In India, for instance, health officials recently identified a strain of TB that is just one drug away from being completely untreatable.

In the new study, scientists showed that in live bacteria treatment with pyridomycin leads to the depletion of fatty acids that are an essential component of the TB cell wall.

"Our finding that pyridomycin kills Mycobacterium tuberculosis... even in clinically isolated bacteria that are resistant to the drug isoniazid, provides a great opportunity to develop pyridomycin or a related agent for the treatment of drug-resistant tuberculosis," remarked Cole.

Wheat Belly: #1 Diet and Health Book in America Changing Lives - ONLY $4.95! Save $21!





© HealthDay

 
1Like our page
2Share
Health-Wire
A natural antibiotic found in bacteria and soil is showing promise as a potential new drug to treat tuberculosis.
tb,antibiotic,drug,resist
328
2012-57-19
Wednesday, 19 Sep 2012 12:57 PM
Newsmax Inc.
 

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved