Tags: metformin | parkinson | diabetes

Diabetes Drug Fights Parkinson’s

Wednesday, 18 Apr 2012 11:48 AM


Metformin – a drug long used to treat diabetes -- can substantially reduce diabetics’ risk of developing Parkinson's disease, a new study has found.
The 12-year study, based on an analysis of Taiwanese patients, found diabetes increases the risk of developing Parkinson's more than twofold. What’s more, the use of sulfonylureas – a class of drugs commonly used to treat diabetes -- increases the risk further by about 57 percent.
But researchers, writing in the journal Parkinsonism and Related Disorders, found patients who also take metformin as part of their therapy had no increased risk of developing Parkinson's.
Metformin, derived from the French lilac Galega officinalis, was first used in traditional European medicine and introduced in the 1950s for the treatment of diabetes, researchers noted. It has a long and safe record, and relatively inexpensive.
“An exciting aspect of the finding is that metformin seems to be working to protect the brain against neurodegeneration which contributes to Parkinsonismin,” said lead researcher Mark Wahlqvist. “This means it may also be considered a relevant therapy for the prevention of dementia as well."


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Metformin can substantially reduce diabetics’ risk of developing Parkinson's disease.
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