Tags: kidney | stones | risks | long | term

Kidney Stones Linked With Long-term Problems

Monday, 03 Sep 2012 02:56 PM


People who get kidney stones have a small but significantly increased risk of developing more serious kidney problems later in life, suggests a study published online in the British Medical Journal.
The study, conducted by a team of American and Canadian researchers, also found women may be at particular risk.
Kidney stones are a common, painful but often preventable condition, but little research has been done to determine if they can lead to end stage renal disease (commonly known as kidney failure) and other problems.
The new study set out to answer that question by tracking 23,706 patients who had at least one kidney stone, for an 11-year period, to see if they had a greater of rate kidney problems.
The results showed the patients had a higher risk of developing late stage chronic kidney disease, kidney failure and increased blood creatinine levels (a sign that the kidneys are not working normally) than people who did not have a history of stones.
Hospital records were used to identify episodes of kidney stones and subsequent development of chronic kidney disease, kidney failure or raised creatinine levels.
The excess risk associated with stones was greater in women than in men and among younger people than in those aged 50 years and over. But the risks of all three adverse outcomes in those with at least one episode of stones were significantly higher than in those without stones in both sexes and age bands.
The researchers said the findings suggest that the calcification process involved in the formation of kidney stones may be a possible cause of later renal damage, while obstruction leading to progressive scarring may also be a factor.
Future research "should be aimed at determining the mechanisms explaining this association and assessing the optimal way to prevent kidney stones in the general population, especially young women," they said.


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People who get kidney stones have an increased risk of developing more serious kidney problems later in life.
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Monday, 03 Sep 2012 02:56 PM
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