Tags: anti | aging | gene | cancer

Anti-aging Gene Fights Tumors

Friday, 21 Dec 2012 12:30 PM


An anti-aging gene has been found to suppress cancer growth, suggesting a potential new way to treat colon and pancreatic tumors.
Although the study, by University of Michigan Health System and Harvard Medical School researchers, involved laboratory mice, the findings could have significant implications for human cancer patients.
The new work, published in the scientific journal Cell, showed a particular genetic protein — known as SIRT6 — can dampen cancer growth and that a loss of the protein leads to an increase in the number, size, and aggressiveness of tumors.
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"It is critical to understand the spectrum of genes that suppress tumor development," said David Lombard, M.D., an assistant professor of pathology and assistant research professor at the UM Institute of Gerontology at the U-M Medical School.
"Our research suggests SIRT6 may have a critical role in blocking cancer and controlling cellular metabolism. We hope to build on this work to better understand how this protein suppresses tumor development, and provide insight into potential future means of reprogramming cancer metabolism."
The research was done in conjunction with the Massachusetts General Hospital Cancer Center at Harvard Medical School. It was funded, in part, by the National Institutes of Health.


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An anti-aging gene has been found to suppress tumors, suggesting a potential new weapon against cancer.
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2012-30-21
Friday, 21 Dec 2012 12:30 PM
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