Tags: vitamin | E | lower | liver | cancer | risk | fat-soluble

Vitamin E Lowers Liver Cancer Risk

Thursday, 19 Jul 2012 12:13 PM


High levels of vitamin E may lower your risk of developing liver cancer, according to a study published in the Journal of the National Cancer Institute. The fat-soluble vitamin, which is found naturally in foods including nuts and vegetable oil, is an antioxidant. Numerous studies have suggested that it may prevent DNA damage.
Dr. Wei Zhang and colleagues analyzed data from a total of 132,837 individuals from two population-based studies jointly conducted by the Shanghai Cancer Institute and Vanderbilt University.
Using food-frequency questionnaires, the researchers conducted in-person interviews to gather data on study participants' dietary habits. Participants were asked how often they ate some of the most commonly consumed foods and whether they took vitamin supplements.
The investigators then compared liver cancer risk among participants who had high intake of vitamin E with those who had low intake. The participants who had higher levels of vitamin E intake, whether from diet or supplements, had a lower risk of liver cancer. The risk was lower for people with and without a history of liver disease or a family history of liver cancer. The participants were followed for up to 10 years.
"We found a clear, inverse dose-response relation between vitamin E intake and liver cancer risk," the authors write.
"Overall, the take home message is that high intake of vitamin E either from diet or supplements was related to lower risk of liver cancer in middle-aged or older people from China," said Xiao Ou Shu, M.D., Ph.D., professor of Medicine at the Vanderbilt Epidemiology Center.
The connection between vitamin C supplements and liver cancer was significantly different. Participants who had the highest vitamin C intake from supplements and who had a family history of liver cancer or self-reported liver disease were more likely to develop liver cancer. There was no link to liver cancer among participants who had the highest levels of vitamin C or other vitamins from food.
The numbers of cases of liver cancer have been rising in the United States. About 28,720 cases of liver cancer will be diagnosed this year, and about 20,550 people will die from the disease in 2012.






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High levels of vitamin E may lower your risk of developing liver cancer, according to a study published in the Journal of the National Cancer Institute.
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2012-13-19
Thursday, 19 Jul 2012 12:13 PM
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