Tags: PSA | screening | saves | lives | prostate-specific | antigen | test

Study: PSA Screening Saves Lives

Thursday, 23 Aug 2012 12:00 PM


Although doctors have chosen sides over the question of benefits versus liabilities of using the prostate-specific antigen (PSA) test to detect prostate cancer, a new study found that routine use of the test has saved lives. A new study published in The Journal of Urology reports that in the "PSA era," survival has improved for patients with newly diagnosed prostate cancer that has spread to the bones or other parts of the body.
A series of three clinical trials over the past three decades evaluated patient survival in patients with prostate cancer who received androgen deprivation treatment (ADT). Two trials took place before the introduction of PSA screening, and one took place after PSA screening and follow-up became widespread. The patients in all three studies were enrolled from cancer centers around the country and eligibility criteria were comparable.
"These sequential trials provide an opportunity to address the question of whether survival has improved since the advent of widespread PSA screening and follow-up testing," says lead investigator Dr. Ian M. Thompson, Jr., Director of the Cancer Therapy and Research Center.
The researchers found a 30 percent decrease in the risk of death for men who were enrolled in the third trial — the one that took place after the introduction of PSA screening. Survival rates were approximately the same for both African American men and non-African American men. In earlier studies, African American men had poorer survival rates.
"Without a doubt," says Dr. Thompson, PSA testing "has played a role in extending many lives."




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Although doctors have chosen sides over the question of benefits versus liabilities of using the prostate-specific antigen (PSA) test to detect prostate cancer, a new study found that routine use of the test has saved lives.
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2012-00-23
Thursday, 23 Aug 2012 12:00 PM
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