Tags: pill | could | replace | needles

Pill Could Replace Needle Injections

By    |   Wednesday, 01 Oct 2014 04:02 PM

Massachusetts Institute of Technology scientists have developed a pill coated with tiny needles that can deliver drugs directly into the lining of the digestive tract — providing a potential alternative to injections.

The development could be useful for many injected drugs that can’t be taken orally because they are broken down in the stomach before they can be absorbed.
 
The new drug capsule is coated with small needles that can inject drugs directly into the lining of the stomach after the capsule is swallowed. In animal studies, the MIT team found that the capsule delivered insulin more efficiently than injection under the skin, and there were no harmful side effects as the capsule passed through the digestive system.
 
“This could be a way that the patient can circumvent the need to have an infusion or subcutaneous administration of a drug,” said Giovanni Traverso, a research fellow at MIT’s Koch Institute for Integrative Cancer Research and a gastroenterologist at Massachusetts General Hospital.
 
Although the researchers tested their capsule with insulin, they said it would be most useful for delivering medications such as antibodies, which are used to treat cancer and autoimmune disorders like arthritis and Crohn’s disease.
 
A report on the pill was published in the Journal of Pharmaceutical Sciences.

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MIT has developed a pill coated with tiny needles that can deliver drugs directly into the lining of the digestive tract.
pill, could, replace, needles
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2014-02-01
Wednesday, 01 Oct 2014 04:02 PM
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