Tags: Alzheimers | tau tangles | amyloid plaque

Scientists Grow Alzheimer's in Lab

By
Friday, 10 Apr 2015 05:05 PM Current | Bio | Archive

Harvard Medical School researchers recently made progress in developing a novel strategy for testing new Alzheimer’s medicines.

The October 12, 2014 online issue of the journal Nature reported that primitive neural stem cells could be grown in a laboratory dish to develop the brain abnormalities of Alzheimer’s disease.

The scientists were able to create both the abnormal amyloid plaque and tau tangle proteins that accumulate in the memory and thinking areas of the brains of Alzheimer’s patients.

Previous lab models created in mice were able to produce plaques or tangles but not both proteins at the same time.

In this new study, the researchers also found that when they increased the levels of a certain enzyme, they could reduce the formation of tau tangles, which can be toxic to brain cells.

Next, the scientists plan to screen large numbers of drugs to see whether they can disrupt the growth of the Alzheimer’s proteins.

Although these findings are of considerable research interest, it is unknown whether this approach will ultimately lead to new drug therapies in patients with the disease.

It can be a long way from a laboratory dish to an effective treatment for a complex disease such as Alzheimer’s.

© 2017 NewsmaxHealth. All rights reserved.

 
1Like our page
2Share
Dr-Small
Harvard Medical School researchers recently made progress in developing a novel strategy for testing new Alzheimer’s medicines.
Alzheimers, tau tangles, amyloid plaque
200
2015-05-10
Friday, 10 Apr 2015 05:05 PM
Newsmax Inc.
 

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved