Tags: grape | seed | kills | leukemia

Grape Seed Compound Kills Leukemia Cells

Wednesday, 31 Dec 2008 09:00 AM

By Sylvia Booth Hubbard

A natural compound extracted from grape seeds makes laboratory leukemia cells commit suicide, according to a new study by the University of Kentucky. When exposed to the extract, 76 percent of the leukemia cells were dead within 24 hours.

The extract forces leukemia cells to commit “apoptosis,” or cell suicide, which is a kind of programmed cell death that cells in the body undergo either in the normal course of growth and development or when something goes wrong with them. Leukemia and other cancers block the cell signaling pathway that allows apoptosis—this is how cancer keeps the defenses of the body at bay. Grape seed extract activates a protein called JNK that regulates the apoptotic pathway and allows damaged cells to commit suicide.

Grape seed extract has already shown beneficial activity in other laboratory cancer cell lines, including breast, skin, lung, and prostate cancers. Before the new study, however, no one had tested the effects of grape seed on hematological cancers, and neither had anyone found the exact mechanism involved.

“What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone, and this shows that grape seed extract fits into this category,” said study author Xianglin Shi, Ph.D., who emphasized that research is still in an early stage. Hematological cancers, including leukemia, caused almost 54,000 deaths in 2006, making them the fourth leading cause of cancer death in the United States.

© 2015 Newsmax. All rights reserved.

Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Rap Mogul Suge Knight Investigated in Deadly Hit-and-Run

Friday, 30 Jan 2015 06:41 AM

Death Row Records founder Marion Suge Knight turned himself into authorities early Friday after his attorney said the  . . .

'Ebola Czar' Ron Klain Will Leave Job Feb. 15

Thursday, 29 Jan 2015 22:32 PM

The Obama administration's "Ebola czar" will leave his post on Feb. 15, although he said there is still work to do at er . . .

Texas Executes Killer Who Claimed Mental Impairment

Thursday, 29 Jan 2015 21:41 PM

The state of Texas on Thursday executed a convicted rapist-killer whose lawyers argued was severely mentally impaired, h . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved