Tumeric Spice, Nausea Drug Destroy Cancer Cells: Study

Wednesday, 21 Aug 2013 04:43 PM

By Nick Tate

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
A compound found in the spice turmeric, when combined with a common anti-nausea drug, has been found to destroy cancers cells in the lab.
 
In a study published in the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers found the one-two punch delivered by curcumin — an active ingredient in the common kitchen spice — and the drug thalidomide effectively creates hybrid molecules that kill multiple myeloma cells.
 
"Although thalidomide disturbs the microenvironment of tumor cells in bone marrow, it disintegrates in the body," said lead researcher Shijun Zhang, assistant professor in the Department of Medicinal Chemistry at the VCU School of Pharmacy. "Curcumin, also active against cancers, is limited by its poor water solubility. But the combination of thalidomide and curcumin in the hybrid molecules enhances both the cytotoxicity and solubility."
 
Editor's Note: Video Exposes Dangers of Obamacare Law

Thalidomide was used in the 1950s to help control morning sickness, but was taken off the shelves in 1962 after it was found to cause birth defects. In the 1990s the drug was re-introduced as a treatment for multiple myeloma. Turmeric has long been used in herbal remedies and is being studied as a potential weapon against cancer, arthritis and Alzheimer's disease.
 
The VCU researchers found the hybrid molecules of turmeric and thalidomide created more created two compounds that effectively induced cancer cells to self-destruct.
 
"Overall, the combination of the spice and the drug was significantly more potent than either individually, suggesting that this hybrid strategy in drug design could lead to novel compounds with improved biological activities," said co-researcher researchers Steven Grant, M.D.

"The results also strongly encourage further optimization of [these] compounds … to develop more potent agents as treatment options for multiple myeloma."

© 2014 NewsmaxHealth. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

Painful Urination: What Does It Mean?

Monday, 14 Apr 2014 01:10 AM

Painful urination includes signs of discomfort, a burning sensation, or anxiety while passing urine. It is more common i . . .

Pancreatic Cancer: Its Symptoms, Awareness, and Treatments

Monday, 14 Apr 2014 00:57 AM

Awareness on pancreatic cancer is quite imperative, since it can give you a chance at a healthy and happy life. Awarenes . . .

Panic and Anxiety Attacks: Symptoms and Disorders

Monday, 14 Apr 2014 00:43 AM

There are different types of medications for panic and anxiety attacks and disorders. In different cases, different medi . . .

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved