Osteoporosis Drug Halts Breast Tumors, Duke Study Finds

Monday, 17 Jun 2013 05:32 PM

By Nick Tate

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
A drug approved in Europe to treat osteoporosis has been shown to stop the growth of breast cancer tumors, including some that can’t be treated by existing therapies.
 
According to a Duke Cancer Institute study, presented this month at the annual Endocrine Society meeting in San Francisco, the drug bazedoxifene packs a powerful one-two punch that not only prevents estrogen from fueling breast cancer cell growth, but also targets the tumor for destruction.
 
"We found bazedoxifene binds to the estrogen receptor [in tumor cells] and interferes with its activity, but the surprising thing we then found was that it also degrades the receptor; it gets rid of it," said lead researcher Donald McDonnell, head of Duke's Department of Pharmacology and Cancer Biology.

Special: Suzanne Somers Found the Doctors Who Beat Cancer
 
The Duke research, which involved animal and human cancer cells, suggests the drug may even be effective in cases where patients are not benefitting from anti-estrogen tamoxifen and/or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen-dependent breast cancer.
 
Currently, if breast cancer cells develop resistance to these drugs, patients have to undergo toxic chemotherapy agents that have significant side effects.
 
The study was funded by a research grant from Pfizer Pharmaceuticals, maker of bazedoxifene.

© 2014 NewsmaxHealth. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

Painful Urination: What Does It Mean?

Monday, 14 Apr 2014 01:10 AM

Painful urination includes signs of discomfort, a burning sensation, or anxiety while passing urine. It is more common i . . .

Pancreatic Cancer: Its Symptoms, Awareness, and Treatments

Monday, 14 Apr 2014 00:57 AM

Awareness on pancreatic cancer is quite imperative, since it can give you a chance at a healthy and happy life. Awarenes . . .

Panic and Anxiety Attacks: Symptoms and Disorders

Monday, 14 Apr 2014 00:43 AM

There are different types of medications for panic and anxiety attacks and disorders. In different cases, different medi . . .

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved