Tags: Obesity | asthma | obesity | gene | link

Are Obesity, Asthma Genetically Linked?

Friday, 19 Jul 2013 01:11 PM

By Nick Tate

New research suggests asthma and obesity may have a common genetic link. The study, conducted by researchers at the University at Buffalo, found genes associated with chronic inflammation in asthma are more active in people who are obese.

The findings suggest losing weight may help treat the chronic lung condition.
"Our findings point the way to the management of asthma in the obese through simple weight reduction," said researcher Paresh Dandona, M.D., an endocrinology, diabetes, and metabolism expert at UB.

Obamacare: Massive New Rules Revealed for 2013
The research, published online in the journal Obesity, involved two related studies: A comparative analysis of the genes of obese people and those of normal weights (60 in all); and an experiment that examined how various biological indicators — including the behavior of asthma-linked genes — changed when morbidly obese patients underwent gastric bypass surgery.
In the comparative study, the scientists found four genes associated with asthma were more active in obese and morbidly obese people, by twice as much in some cases. The scientists also found higher concentrations of two asthma-related compounds in the blood of obese and morbidly obese patients.
In the second study, researchers found the activity of at least six asthma-related genes decreased in patients who underwent gastric bypass surgery to lose weight.
"Ours is the first study to provide a mechanistic link between obesity and asthma through biological/immunological mechanisms," Dr. Dandona said. "There has been, until now, no biological, mechanistic explanation other than the fact that obesity may raise the diaphragm and thus reduce lung volumes."

© 2015 NewsmaxHealth. All rights reserved.

Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
Zip Code:
Privacy: We never share your email.
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

A-Fib Found to Double 'Silent' Stroke Risk

Monday, 24 Nov 2014 14:14 PM

Atrial fibrillation, a common condition in which the heart beats irregularly, more than doubles the risk of "silent stro . . .

Drug to Treat Hemophilia

Friday, 24 Oct 2014 12:48 PM

Drugmaker Baxter International Inc said the U.S. Food and Drug Administration had approved its drug for treating bleedin . . .

4 Things You Need to Know About This Year's Flu Shot

Thursday, 04 Sep 2014 10:58 AM

At this point, scientists say they can't predict the severity of the coming flu season. But if you are planning to get t . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

America's News Page
©  Newsmax Media, Inc.
All Rights Reserved