Tags: Cancer | Colorectal Cancer Genes Discovered

Colorectal Cancer Genes Discovered

Thursday, 21 Feb 2013 04:27 PM

By Nick Tate

An international research team has linked a small number of genes to an increased risk of colorectal cancer. The team, led by the Fred Hutchinson Cancer Research Center, said people with defects in the genes are up to 40 percent more likely to develop the life-threatening disease than those without.

Researchers said the study, published online in the journal of Gastroenterology, could lead to dramatic improvements in doctors’ ability to identify people at greater risk of developing the cancer and point the way to new diagnostic tests and drugs to target the DNA defects.
"These findings could potentially lead to new drug targets and, in combination with previously identified genetic and environmental risk factors, identify subgroups of the population that can benefit most from colorectal-cancer screening and could be targeted for early or more frequent endoscopy, a very effective screening tool for colorectal cancer," said Ulrike "Riki" Peters, a cancer-prevention specialist at Fred Hutch who helped direct the study.

Alert: The Two Signs Your Heart Is In Trouble
Peters and colleagues from 40 institutes around the world have been studying genes linked to colorectal cancer for the past four years, analyzing data from approximately 40,000 study participants, half of whom have the disease.
The team scanned blood DNA from 12,696 people with colorectal cancer or a precancerous condition called adenoma and compared the results to the DNA from 15,113 other healthy people. The scans identified 2.7 million genetic defects, 10 of which were associated with colorectal cancer.
The researchers said their findings indicate people with one or two of the genetic variants face a 10-40 percent increased risk of developing colorectal cancer than individuals without them.
The study was funded, in part, by the National Cancer Institute, the National Institutes of Health, and the U.S. Department of Health and Human Services.

© 2015 NewsmaxHealth. All rights reserved.

Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
Zip Code:
Privacy: We never share your email.
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Is Too Much Calcium Killing You?

Tuesday, 27 Jan 2015 16:22 PM

We need lots of calcium for strong bones, especially as we age. Or do we? A top doctor is questioning the conventional  . . .

A-Fib Found to Double 'Silent' Stroke Risk

Monday, 24 Nov 2014 14:14 PM

Atrial fibrillation, a common condition in which the heart beats irregularly, more than doubles the risk of "silent stro . . .

Drug to Treat Hemophilia

Friday, 24 Oct 2014 12:48 PM

Drugmaker Baxter International Inc said the U.S. Food and Drug Administration had approved its drug for treating bleedin . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

America's News Page
©  Newsmax Media, Inc.
All Rights Reserved