New Drug Cures Some Blood Cancer Patients in Trials

Friday, 08 Nov 2013 12:59 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink

Geron Corp said 22 percent of trial patients treated with its experimental blood cancer drug were now free of the disease, a major break for the company after two big setbacks.
Shares of Geron more than doubled in morning trade on Thursday to a four-year high.
"This is going to save the company, because it's the last thing that they had," MLV & Co analyst George Zavoico told Reuters. "This truly opens the door for other opportunities in other indications."
Geron earlier failed to develop the blood cancer drug, imetelstat, to treat breast cancer. It also stopped working on its brain cancer drug.
Imetelstat is designed to treat myelofibrosis, a rare form of blood cancer.
Zavoico said the data validated imetelstat's "mechanism of action" and suggested it was superior to Incyte Corp's Jakafi, which is approved to treat myelofibrosis.
Imetelstat is designed to inhibit telomerase, an enzyme that enables rapid multiplication of cancer cells.
Jakafi inhibits another family of enzymes, reducing cell multiplication. The drug had sales of $136 million in 2012.
Zavoico said Jakafi reduced spleen size and relieved symptoms, but did not have a disease-modifying effect, defined as partial or complete remission.
Geron said one patient of the first 18 enrolled in the trial showed partial remission.
The company released the data ahead of a presentation on December 9 at the annual meeting of the American Society of Hematology.
 

© 2014 Thomson/Reuters. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

ER Study: Too Many Kids Prescribed Codeine

Monday, 21 Apr 2014 08:28 AM

Despite recommended limits on codeine use in children, the potent painkiller is prescribed for children in at least half . . .

Yoga Eases PTSD Symptoms: Study

Monday, 21 Apr 2014 08:18 AM

Women enrolled in a small study reported a reduction in symptoms of post-traumatic stress disorder (PTSD) after a series . . .

Goodbye, Bulk: Today's Strength Training Is for Slimming Down

Monday, 21 Apr 2014 08:06 AM

Strength training, traditionally favored by body builders seeking to bulk up, has become the go-to regimen for athletes, . . .

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved