Melanoma Drug Effective in Trials

Monday, 18 Nov 2013 04:57 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
Early data from a small trial of Merck & Co Inc's experimental immunotherapy cancer drug, known as MK-3475, show that about half of advanced melanoma patients treated with the highest dose of the drug experienced tumor shrinkage.

Updated results from the early-stage trial are set to be presented on Monday at the International Congress of the Society for Melanoma Research in Philadelphia.

The antibody drug is part of a new class of compounds designed to block the activity of a receptor on immune cells called programmed death 1, or PD-1. The aim of the drugs is to spur the body's own immune system to attack cancer cells.

Merck said results from 135 patients whose melanoma had stopped responding to earlier rounds of treatment showed that 41 percent had tumor shrinkage - the rate was 51 percent in the high-dose group, and 40 percent for lowest-dose group.

The company estimated overall survival at a year of treatment at 81 percent, but said the trial had not yet reached either a median duration of response or median overall survival.

Serious side effects seen in the trial included fatigue, rash, increased liver enzymes and renal
failure.

© 2014 Thomson/Reuters. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Daily Aspirin Cuts Prostate Cancer Risk: Study

Tuesday, 30 Sep 2014 12:06 PM

Men who take a daily dose of aspirin or similar anti-inflammatory medicine may also reduce their risk of developing pros . . .

Did A-Bomb Test Give New Mexico Residents Cancer?

Tuesday, 30 Sep 2014 12:02 PM

Researchers from the National Cancer Institute want to know how many past and present cancer cases in New Mexico may be  . . .

Granny Smith Apples Keep You Slim: Study

Tuesday, 30 Sep 2014 11:58 AM

Non-digestible compounds found in apples promote the growth of friendly gut bacteria, which stabilizes the metabolism an . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved