Scientists Find Way to 'Switch Off' High Blood Pressure

Tuesday, 23 Jul 2013 02:39 PM

By Nick Tate

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
A team of California researchers has identified a molecular "on-off switch" that regulates high blood pressure — a finding that could provide a new key to controlling and preventing the biological processes that trigger the deadly condition.
 
In a new report published online this month in the journal Bioorganic & Medicinal Chemistry, the University of California-San Diego team said it has designed new compounds that mimic those naturally used by the body to regulate blood pressure.
 
Editor’s Note: Cure High Blood Pressure Without Drugs, in 8 Weeks

The work could pave the way for a new class of drug treatments for hypertension, which affects about 76 million people — about one in three adults — in the United States, according to the American Heart Association. Untreated, it can damage blood vessels and lead to kidney failure, heart attack, and stroke.
 
"This approach demonstrates the effectiveness of rational design of novel drug candidates," said lead researcher Igor F. Tsigelny, a scientist with the university's San Diego Supercomputer Center, the UC-San Diego Moores Cancer Center, and the Department of Neurosciences.
 
For the study, scientists focused on a particular peptide — called catestatin — that they determined to be a key "gatekeeper" compound involved in the regulation of hypertension. They said a drug that can mimic the action of catestatin would allow people to control the hormones that regulate blood pressure.
 
"Our results suggest that analogs can be designed to match the action of catestatin, which the body uses to regulate blood pressure," added Daniel T. O'Connor, a professor at the UC-San Diego School of Medicine. "Those designer analogs could ultimately be used for treatment of hypertension or autonomic dysfunction."

© 2014 NewsmaxHealth. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Dark Days Here for Those With Seasonal Depression

Saturday, 25 Oct 2014 09:36 AM

October's shorter, darker days can trigger a type of depression, known as seasonal affective disorder, according to an e . . .

Doctor With Ebola Was Very Careful: Colleagues

Saturday, 25 Oct 2014 09:31 AM

An American doctor who caught Ebola while treating patients in Guinea was a hard worker who conscientiously followed saf . . .

Violinist Itzhak Perlman: Time to Wipe Out Polio Forever

Friday, 24 Oct 2014 15:17 PM

Itzhak Perlman says the world needs to wipe out the curse of polio once and for all , and the beloved violin virtuoso, s . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved