Gum Disease Can Lead to Arthritis: Study

Friday, 13 Sep 2013 03:55 PM

By Nick Tate

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
Gum disease can lead to joint problems. That's the key finding of new research, published in the Public Library of Science journal PLOS Pathogens, that shows the bacterium responsible for periodontal disease worsens rheumatoid arthritis by speeding its development and progression, and causing more severe symptoms.
 
University of Louisville School of Dentistry researchers noted clinicians have long known the two chronic inflammatory conditions are linked, but the new study is among the first to identify the microbiological culprit — Porphyromonas gingivalis — as the connection.
 
"Taken together, our results suggest that bacterial [agents] may constitute the mechanistic link between P. gingivalis periodontal infection and rheumatoid arthritis," said Jan Potempa, a Louisville specialist who headed the international team of scientists from the European Union's Gums and Joints project that made the discovery. "But this ground-breaking conclusion will need to be verified with further research."
 
The scientists found that the gum disease microbe produces a unique enzyme that promotes collagen-induced arthritis — a form of arthritis similar to RA — which, in turn, prompts an immune system attack. In arthritis patients, this leads to chronic inflammation and bone and cartilage destruction within the joints.
 
Potempa said he is hopeful these findings could lead to new treatments and prevention strategies for arthritis.
 
Past studies have shown people with gum disease have twice the risk of developing arthritis, compared to the general population. 

© 2014 NewsmaxHealth. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Indoor Fall Is Danger Sign for Seniors: Study

Thursday, 18 Sep 2014 17:06 PM

Women in their eighties who fell indoors, rather than outdoors or from a height like a ladder, died sooner than their pe . . .

One Dose of Antidepressant Changes Brain Connections: Study

Thursday, 18 Sep 2014 17:01 PM

Just a single dose of a common antidepressant can quickly alter theway brain cells communicate with one another, early r . . .

Researchers: Sit Less, Live Longer

Thursday, 18 Sep 2014 15:30 PM

New research shows that sitting less can slow the aging process and contribute to longer life. The findings, from two ne . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved