New Gene Therapy Found to Reverse Heart Failure

Thursday, 14 Nov 2013 04:42 PM

By Nick Tate

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
Mt. Sinai researchers are testing a powerful gene therapy, delivered directly into the heart, that has been shown in preliminary studies to reverse heart failure.
 
The preclinical findings, reported by heart specialists at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, have shown that the so-called SUMO-1 gene therapy shrinks an enlarged heart, improves heart function, and increases blood flow.
 
"SUMO-1 gene therapy may be one of the first treatments that can actually shrink enlarged hearts and significantly improve a damaged heart's life-sustaining function," said Roger J. Hajjar, M.D., who led the study, published in the journal Science Translational Medicine.

SPECIAL: These 4 Things Happen Right Before a Heart Attack — Read More.

"We are very eager to test this gene therapy in our patients suffering from severe heart failure."
 
Dr. Jajjar said the researchers now hope to begin human clinical trials of SUMO-1, which is named after a gene that is "missing in action" in heart failure patients. It is the second potential gene therapy technique developed by Dr. Jajjar's team.
 
Heart failure is a leading cause of hospitalization in the elderly, accounting for about 300,000 deaths each year in the United States. It occurs when a person's heart is too weak to pump and circulate blood.
 
The study was funded, in part, by the National Institutes of Health.

© 2014 NewsmaxHealth. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

FDA OKs New Blood Cancer Drug

Wednesday, 23 Jul 2014 17:02 PM

The U.S. Food and Drug Administration said on Wednesday it has approved Gilead Sciences Inc's Zydelig, a drug to treat t . . .

4 in 5 Americans Have Multiple Life-Shortening Health Problems: Study

Wednesday, 23 Jul 2014 14:05 PM

Life expectancy in the U.S. is rising more slowly than other parts of the world, and new research out of Johns Hopkins s . . .

Rosemary, Oregano May Fight Diabetes: Study

Wednesday, 23 Jul 2014 13:58 PM

Oregano and rosemary have been found to contain compounds that may help ward off diabetes. New research shows the popula . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved