Scientists Create Dust Mite Allergy Vaccine

Thursday, 24 Jul 2014 12:30 PM


  Comment  |
   Contact  |
  Print   |
    A   A  
  Copy Shortlink

A research team at the University of Iowa has created a vaccine whose key ingredient, normally used in cancer vaccines, could be effective in provoking natural immune responses that combat dust mite allergies.
According to the study, the package contains a booster that ignites anti-inflammatory response to the microscopic mites which, when amassed by the millions, could resemble dust and cause breathing difficulties even for those who aren't allergic.
Reported to exist in 84 percent of US households, dust mites inhabit mattresses, sofas and rugs, which offer them frequent access to human skin, triggering allergies and breathing problems.
Young asthmatics are particularly sensitive to dust mites and, according to guidelines from the American College of Allergy, Asthma & Immunology, 45 percent are allergic to them.
"This work suggests a way forward to alleviate mite-induced asthma in allergy sufferers," says contributing author Peter Thorne, a public health professor at UI.
The key ingredient in the booster has been successfully used in cancer vaccines and the study in question represents its first use in a dust mite allergy vaccine.
Called CpG, the adjuvant (booster) calls immune cells into action and, in turn, the activated immune cells imbibe it, thereby unleashing the vaccine carried by the CpG particles.
Upon reception of the vaccine, immune cells perform their anti-inflammatory duties and later dispose of the CpG particles.
"Our research explores a novel approach to treating mite allergy in which specially-encapsulated miniscule particles are administered with sequences of bacterial DNA that direct the immune system to suppress allergic immune responses," says Thorne.
The research team is currently at work on further testing of the vaccine in hopes that it will soon be available to those who suffer from dust mite allergies.
The study was published in American Association of Pharmaceutical Scientists (AAPS) Journal.

© AFP/Relaxnews 2014

  Comment  |
   Contact  |
  Print   |
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
Zip Code:
Privacy: We never share your email.
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Statin-Antibiotic Combination Can Be Deadly

Monday, 22 Dec 2014 16:31 PM

Seniors who take the antibiotic Biaxin (clarithromycin) along with certain types of cholesterol-lowering statins are at  . . .

New Technique Restores Memories Lost to Alzheimer's

Monday, 22 Dec 2014 16:30 PM

UCLA researchers have developed a way to regenerate damaged connections between brain cells - an approach that could one . . .

Hockey Legend Gordie Howe Undergoes Stem Cell Treatment

Monday, 22 Dec 2014 16:26 PM

Hockey star Gordie Howe has undergone stem cell treatment after suffering a series of strokes this year, according to hi . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

America's News Page
©  Newsmax Media, Inc.
All Rights Reserved