No More Colonoscopies? Noninvasive Test Found Effective

Thursday, 18 Apr 2013 12:25 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink
Exact Sciences Corp said its molecular screening test for colorectal cancer met a late-stage trial goal of detecting the disease in more patients than other commonly used tests, but shares fell 28 percent as the results were not as robust as some were expecting.
 
Exact's test, which identifies abnormal DNA in cells shed in a patient's stool, detected 92 percent of colorectal cancers and 42 percent of pre-cancerous polyps in a large late-stage study.
 
"Pre-cancerous sensitivity, which was the key metric investors were looking at, was well below expectations," Wedbush Securities analyst Zarak Khurshid said, adding that "lower pre-cancer sensitivity may limit the eventual addressable opportunity for the test."
 
Khurshid was expecting a 55 percent detection rate for pre-cancerous polyps.
 
Exact's non-invasive test was developed to be a more accurate alternative to currently available non-invasive screenings.
 
The study compared the performance of its Cologuard test to colonoscopy and fecal immunochemical testing that looks for blood in a stool sample.
 
While a colonoscopy is considered the most accurate method of detecting colon cancer and polyps, many people avoid the recommended test as it involves inserting a flexible tube into the colon.
 
The trial was conducted on 10,000 patients between the ages of 50 and 84 years, who were at average risk for colorectal cancer.
 
Madison, Wisconsin-based Exact Sciences plans to submit the study data to the U.S. Food and Drug Administration as part of its approval application.
 
Colorectal cancer is the third most commonly diagnosed cancer in the United States, responsible for about 50,000 deaths a year.

© 2014 Thomson/Reuters. All rights reserved.

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

9 Healthy Habits You Can Do in One Minute or Less

Wednesday, 23 Apr 2014 10:53 AM

Healthy habits don't have to be a challenge, nor do they have to take a big chunk out of your day. Many changes to your  . . .

Help for Men's Sex Woes Are Not Always in a Pill

Wednesday, 23 Apr 2014 08:36 AM

A new study reminds men with erectile dysfunction that there's help out there that doesn't require a prescription: diet, . . .

Blood Cancer Drug Shows Effectiveness

Wednesday, 23 Apr 2014 08:26 AM

Spectrum Pharmaceuticals Inc said its experimental blood cancer drug was shown to be safe and effective in a mid-stage t . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved