Simple Blood Test Warns of Breast Cancer

Friday, 27 Jun 2014 12:15 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink

Women with a predisposition to breast cancer could be warned of developing symptoms by a simple blood test even if they do not inherit genes associated with disease, scientists said on Friday.
 
Research has identified a molecular "switch" in blood samples that makes a woman vulnerable to breast cancer.
 
The marker is linked to the BRCA1 breast cancer gene but was also present in those who did not have the mutation and later developed the disease.
 
BRCA1 and BRCA2 variants are responsible for 10 percent of breast cancers and are inherited from parents.
 
A woman with the BRCA1 gene has an 85 percent risk of developing breast cancer, resulting sometimes in the drastic step of breast removal.
 
This leaves around 90 percent of breast cancer cases unexplained with no credible way of predicting the likelihood of non-inherited breast cancer.
 
Scientists claim that the "switch" is part of the process by which certain molecules acting on DNA cause genes to be activated or deactivated.
 
"We identified an epigenetic signature in women with a mutated BRCA1 gene that was linked to increased cancer risk and lower survival rates," lead researcher Professor Martin Widschwendter, from University College London, said.
 
"Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.
 
"The data is encouraging since it shows the potential of a blood-based epigenetic test to identify breast cancer risk in women without known predisposing genetic mutations."
 
For their research the scientists analyzed blood sample DNA from 119 postmenopausal women who later developed the disease over a period of up to 12 years, and 122 who remained cancer-free.

© AFP 2014

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Sedentary Lifestyle Linked to Depression

Friday, 19 Sep 2014 08:08 AM

A new analysis of previous studies ties too much sitting at the computer or lying around watching TV to a greater risk o . . .

Study: Angelina Jolie Surgery Sparks Surge in Cancer Tests

Friday, 19 Sep 2014 08:02 AM

Hollywood star Angelina Jolie's decision to make public her double mastectomy more than doubled the number of women in B . . .

Which Flu Shot Is Right for You?

Friday, 19 Sep 2014 07:55 AM

It's time for flu vaccine again and while it's important for the whole family, this year health officials have some diff . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved