Simple Blood Test Warns of Breast Cancer

Friday, 27 Jun 2014 12:15 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink

Women with a predisposition to breast cancer could be warned of developing symptoms by a simple blood test even if they do not inherit genes associated with disease, scientists said on Friday.
 
Research has identified a molecular "switch" in blood samples that makes a woman vulnerable to breast cancer.
 
The marker is linked to the BRCA1 breast cancer gene but was also present in those who did not have the mutation and later developed the disease.
 
BRCA1 and BRCA2 variants are responsible for 10 percent of breast cancers and are inherited from parents.
 
A woman with the BRCA1 gene has an 85 percent risk of developing breast cancer, resulting sometimes in the drastic step of breast removal.
 
This leaves around 90 percent of breast cancer cases unexplained with no credible way of predicting the likelihood of non-inherited breast cancer.
 
Scientists claim that the "switch" is part of the process by which certain molecules acting on DNA cause genes to be activated or deactivated.
 
"We identified an epigenetic signature in women with a mutated BRCA1 gene that was linked to increased cancer risk and lower survival rates," lead researcher Professor Martin Widschwendter, from University College London, said.
 
"Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.
 
"The data is encouraging since it shows the potential of a blood-based epigenetic test to identify breast cancer risk in women without known predisposing genetic mutations."
 
For their research the scientists analyzed blood sample DNA from 119 postmenopausal women who later developed the disease over a period of up to 12 years, and 122 who remained cancer-free.

© AFP 2014

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Retype Email:
Country
Zip Code:
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
You May Also Like

US to Begin Testing Ebola Vaccine

Friday, 01 Aug 2014 12:36 PM

The U.S. government will begin testing on people an experimental Ebola vaccine as early as September, after seeing posit . . .

Smoking at Higher Risk for Blindness: Johns Hopkins Study

Friday, 01 Aug 2014 12:31 PM

People who smoke, or have smoked a large number of cigarettes over time, are more likely to develop age-related macular  . . .

Blue-Collar Jobs Have Higher Heart Risks

Friday, 01 Aug 2014 12:28 PM

Stress at work may raise your risk of heart attack and stroke, particularly if you work in the service industry or have  . . .

Most Commented

Newsmax, Moneynews, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, NewsmaxWorld, NewsmaxHealth, are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved