Simple Blood Test Warns of Breast Cancer

Friday, 27 Jun 2014 12:15 PM

 

Share:
  Comment  |
   Contact Us  |
  Print  
|  A   A  
  Copy Shortlink

Women with a predisposition to breast cancer could be warned of developing symptoms by a simple blood test even if they do not inherit genes associated with disease, scientists said on Friday.
 
Research has identified a molecular "switch" in blood samples that makes a woman vulnerable to breast cancer.
 
The marker is linked to the BRCA1 breast cancer gene but was also present in those who did not have the mutation and later developed the disease.
 
BRCA1 and BRCA2 variants are responsible for 10 percent of breast cancers and are inherited from parents.
 
A woman with the BRCA1 gene has an 85 percent risk of developing breast cancer, resulting sometimes in the drastic step of breast removal.
 
This leaves around 90 percent of breast cancer cases unexplained with no credible way of predicting the likelihood of non-inherited breast cancer.
 
Scientists claim that the "switch" is part of the process by which certain molecules acting on DNA cause genes to be activated or deactivated.
 
"We identified an epigenetic signature in women with a mutated BRCA1 gene that was linked to increased cancer risk and lower survival rates," lead researcher Professor Martin Widschwendter, from University College London, said.
 
"Surprisingly, we found the same signature in large cohorts of women without the BRCA1 mutation and it was able to predict breast cancer risk several years before diagnosis.
 
"The data is encouraging since it shows the potential of a blood-based epigenetic test to identify breast cancer risk in women without known predisposing genetic mutations."
 
For their research the scientists analyzed blood sample DNA from 119 postmenopausal women who later developed the disease over a period of up to 12 years, and 122 who remained cancer-free.

© AFP 2014

Share:
  Comment  |
   Contact Us  |
  Print  
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Hot Topics
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Female Bosses Prone to Depression: Study

Friday, 21 Nov 2014 23:11 PM

Being the boss at work seems to raise the odds for symptoms of depression among women, but not men, a new study finds.  . . .

Olive Oil Linked to Dramatic Heart Benefits

Friday, 21 Nov 2014 17:45 PM

Regular consumption of olive oil can drastically improve heart health - especially in people who have recently switched  . . .

Woman Dies After Metal Detector Causes Pacemaker to Malfunction

Friday, 21 Nov 2014 17:38 PM

An airport metal detector caused a woman's pacemaker to malfunction and kill her while she was traveling with her husban . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved