Tuberculosis: Top 5 Drugs

Thursday, 11 Nov 2010 12:47 PM

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In the last few years, newer strains of tuberculosis have been cropping up all over the world. The tuberculosis bacterium has evolved with the human race and over the ages, so newer and better tuberculosis drugs have been developed to deal with the evolving bacterium.
 
Treating tuberculosis with tuberculosis drugs
Newer and better drugs are required to treat TB. Better drugs can lessen the tuberculosis therapy time, can treat latent TB infections, and can also improve the treatment and resolution of antibiotic-resistant TB. If you think you have TB, get in touch with a physician who could carry out a simple tuberculosis skin test. A positive result will indicate exposure to the disease, but further tests may be required to confirm existence of the disease. Here is a list of the top five most popular tuberculosis drug treatment medications that are currently used:
  1. Isoniazid and Rifampin are given to almost all patients who test positive. Recently, most physicians have noticed an increased resistance to these two drugs. At least one in seven cases is resistant to this first group of tuberculosis drugs. Patients who have acquired Primary Drug Resistant TB will have to be started on newer groups of tuberculosis drugs.
  2. Streptomycin sulphate, Pyrazinamide, and ethambutol HCL are another group of drugs that are used for active TB and for latent tuberculosis treatment. Most doctors will prescribe a combination of Isoniazid, Rifampin, Streptomycin Sulphate, Pyrazinamide, and Ethambutol HCL as a first line of treatment for the disease.
  3. The next group of TB drugs include amino glycosides, polypeptides, fluoroquinolones, thioamides, ethionamide, prothionamide, cycloserine, and p-aminosalicylic acid. These groups are used only when the patients cannot tolerate the first line of tuberculosis drugs.
  4. The next line of tuberculosis drugs includes macrolides, rifabutin, linezolid, and thioridazine. These drugs are commonly used but they are not approved by the World Health Organization.
  5.  A few drugs that show better results include Diarylquinoline and Pyrroles.

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