Tags: Cancer | xgeva | bone | tumor | gctb

New Medication Fights Bone Tumors

Friday, 14 Jun 2013 03:23 PM

 

  Comment  |
   Contact  |
  Print   |
    A   A  
  Copy Shortlink
Xgeva (denosumab) has been approved by the U.S. Food and Drug Administration to treat giant cell tumor of the bone (GCTB), a rare tumor that's most often non-cancerous.

The tumor usually affects adults between ages 20 and 40, although it may also develop in adolescents, the FDA said. It typically doesn't spread, although in rare cases it can become cancerous and travel to the lungs.
 
As a non-cancerous tumor, GCTB destroys bone as it becomes larger, causing pain, fractures, and loss of mobility. Xgeva has been approved in cases where the tumor can't be surgically removed, or might lead to a severe outcome such as loss of a limb, the agency said.
 
Xgeva, approved under the FDA's expedited review program, was evaluated for this use in two clinical trials involving a total of 305 adults and adolescents. Common side effects included joint pain, headache, nausea, fatigue, back pain, and extremity pain.
 
Women of childbearing potential should use "highly effective" contraception while taking Xgeva, since the drug can harm a fetus, the FDA warned.
 
The drug was first approved in 2010 to prevent fractures when cancer has spread to the bone. It's marketed by Amgen, based in Thousand Oaks, Calif.

© HealthDay

  Comment  |
   Contact  |
  Print   |
  Copy Shortlink
Around the Web
Join the Newsmax Community
Please review Community Guidelines before posting a comment.
>> Register to share your comments with the community.
>> Login if you are already a member.
blog comments powered by Disqus
 
Email:
Country
Zip Code:
Privacy: We never share your email.
 
Follow Newsmax
Like us
on Facebook
Follow us
on Twitter
Add us
on Google Plus
Around the Web
Top Stories
You May Also Like

Device Makes Blood Transfusions Safer

Wednesday, 17 Dec 2014 13:08 PM

U.S.health regulators on Tuesday approved a device developed by Cerus to reduce the risk of infections in blood plasma t . . .

New Drug Fights Hormonal Disorder

Tuesday, 16 Dec 2014 08:12 AM

U.S. health regulators have approved Novartis' drug Signifor LAR as a treatment for a rare and life-threatening hormonal . . .

Blood Test Reveals Heart Risk

Monday, 15 Dec 2014 16:31 PM

The U.S. Food and Drug Administration on Monday approved a new blood test that can help determine a person's future odds . . .

Most Commented

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

 
NEWSMAX.COM
America's News Page
©  Newsmax Media, Inc.
All Rights Reserved